Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University

Graduate School of Chemical Sciences and Engineering, Hokkaido University

Molecular Chemistry and Engineering Course / Chemical Reaction Development Laboratory

Mita Group

We are working on developing a novel method for synthesizing high-value compounds by activating small molecules.

To this end, we effectively utilize visible light, electrochemical techniques, or transition metal catalysts,

while incorporating computational chemistry into reaction development.

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Welcome to the Mita Group!

Our group is studying new synthetic methods for generating value-added compounds from inexpensive, abundant molecules, focusing particularly on the development of radical or carbene reactions using visible light, electrochemical techniques, or transition metal catalysts. To accelerate the development of these new chemical reactions, our study leverages computational tools, specifically quantum chemical calculations with automated reaction path search algorithms, in collaboration with the Satoshi Maeda group at Hokkaido University.

News / Awards

Photoredox-Catalyst-Free Carboxylation of Unactivated Alkenes in DMSO: Synthesis of Polycyclic Indole Derivatives and Aliphatic Acids

Debbarma, S.; Hayashi, H.; Ueno, Y.; Kanna, W.; Tanaka, K., III; Mita, T.* Org. Lett. 2024, 26, 10897 - 10902.

DOI : 10.1021/acs.orglett.4c04051
Annulation Producing Diverse Heterocycles Promoted by Cobalt Hydride
Sugimura, T.; Yamada, R.; Kanna, W.; Mita, T.; Maeda, S.; Szarłan, B.; Shigehisa, H.* ACS Catal. 2024, 14, 15514 - 15520.

DOI : 10.1021/acscatal.4c05195
- Preprint (ChemRxiv) DOI: 10.26434/chemrxiv-2024-1csmc-v2
Strain-Releasing Ring-Opening Diphosphinations for the Synthesis of Diphosphine Ligands with Cyclic Backbones

Krishnan, C. G.; Takano, H.; Katsuyama, H.; Kanna, W.; Hayashi, H.; Mita, T.* JACS Au 2024, 4, 3777 - 3787.

DOI : 10.1021/jacsau.4c00347